标签：延伸因子EF-1δ抗体 古朵生物 抗原抗体

　　古朵阐述：延伸因子EF-1δ抗体应用方法

　　中文名称 延伸因子EF-1δ抗体

　　英文名称 EEF1D

　　别 名 Antigen NY CO 4; Antigen NY-CO-4; EEF 1D; EEF1D; EF 1 delta; EF 1D; EF-1-delta; EF1D; EF1D_HUMAN; Elongation factor 1 delta; Elongation factor 1-delta; Eukaryotic translation elongation factor 1 delta; Guanine nucleotide exchange protein.

　　研究领域 细胞生物 转录调节因子 转运蛋白 表观遗传学

　　抗体来源 Rabbit

　　克隆类型 Polyclonal

　　交叉反应 Human, Mouse, Rat, Chicken, Pig, Cow, Horse, Rabbit, Sheep,

　　产品应用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 延伸因子EF-1δ抗体(石蜡切片需做抗原修复)

　　not yet tested in other applications.

　　optimal dilutions/concentrations should be determined by the end user.

　　分 子 量 31kDa

　　性 状 Lyophilized or Liquid

　　浓 度 1mg/1ml

　　免 疫 原 KLH conjugated synthetic peptide derived from human EEF1D

　　亚 型 IgG

　　纯化方法 affinity purified by Protein A

　　储 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4

　　保存条件 Store at -20 亱C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20亱C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 亱C.

　　延伸因子EF-1δ抗体产品介绍 background:

　　This gene encodes a subunit of the elongation factor-1complex, which is responsible for the enzymatic delivery ofaminoacyl tRNAs to the ribosome. This subunit, delta, functions asguanine nucleotide exchange factor. It is reported that followingHIV-1 infection, this subunit interacts with HIV-1 Tat. Thisinteraction results in repression of translation of host cellproteins and enhanced translation of viral proteins. Severalalternatively spliced transcript variants encoding multipleisoforms have been found for this gene. Related pseudogenes havebeen defined on chromosomes 1, 6, 7, 9, 11, 13, 17, 19.[provided byRefSeq, Aug 2010].

　　Function:

　　EF-1-beta and EF-1-delta stimulate the exchange of GDP bound to EF-1-alpha to GTP.

　　Subunit:

　　EF-1 is composed of 4 subunits: alpha, beta, deltaisoform 1, and gamma. Isoform 2 interacts with HSF1 and NFE2L2.

　　Subcellular Location:

　　Isoform 2: Nucleus.

　　Tissue Specificity:

　　Isoform 2 is specifically expressed in brain,cerebellum and testis.

　　Post-translational modifications:

　　Phosphorylated upon DNA damage, probably by ATM or ATR.

　　Similarity:

　　Belongs to the EF-1-beta/EF-1-delta family.

　　Database links:

　　UniProtKB/Swiss-Prot: P29692.5

　　Important Note:

　　This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

　　古朵阐述：延伸因子EF-1δ抗体应用方法 古朵一直视质量控制为企业的生命，追求企业竞争力的不断提升。公司始终秉承信誉为生存之本的宗旨，以过硬的质量和优良的服务来维护和拓展市场，较大限度的满足客户的需求。与客户的共赢，是我们的发展目标。古朵!您信任的合作伙伴。我们愿与您真诚合作，共创美好的未来。